Ever Young™

Looking for the ultimate Anti-Aging supplement? Then you have to try Baseline Nutritionals'® Ever Young™-- anti-aging nutrition and protection for every single cell and organ in your body.

Anti-Aging Supplement to Support Cell Rejuvenation, Protection for All Organs & Anti Aging Nutrition:

  • May nutritionally extend cell life and promote a younger appearance.
  • Can support the reduction of organ damage caused by protein cross-linking and excess sugar in the blood.
  • May inactivate beta-amyloid plaque in the brain, which may promote long-term brain health and functionality.
  • Helps optimize the body's muscle/nerve/biochemical balance.
  • Supports the body's ability to neutralize factors that may contribute to involuntary muscle movement! 
  • Contains leading anti-aging ingredients including DMAE, Carnosine, and Acetyl-l-Carnitine.
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The ingredients in Ever Young™ may extend the life of cells, reduce and reverse protein and organ damage caused by excess sugar in the blood and cross-linking, inactivate beta-amyloid plaque in the brain, and nutritionally support the body's ability to reverse some of the factors that contribute to muscle tremors.*

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Reports:

Ingredient Supporting Studies:

1. McFarland, G.A., R. Holliday. "Retardation of the Senescence of Cultured Human Diploid Fibroblasts by Carnosine." Exp Cell Res 212:2 (1994): 167--175. <http://www.ncbi.nlm.nih.gov/pubmed/8187813>

2. McFarland, G.A., R. Holliday. "Further Evidence for the Rejuvenating Effects of the Dipeptide L-Carnosine on Cultured Human Diploid Fibroblasts." Exp Gerontol 34:1 (1999): 35--45. <http://www.ncbi.nlm.nih.gov/pubmed/10197726>

3. Yuneva, M.O., E.R. Bulygina, S.C. Gallant, et al. "Effect of Carnosine on Age induced Changes in Senescence-accelerated Mice." J Anti-Aging Med 2:4 (1999):  337--342. <http://online.liebertpub.com/doi/abs/10.1089/rej.1.1999.2.337>

4. Boldyrev, A., R. Song, D. Lawrence, et al. "Carnosine Protects Against Excitotoxic Cell Death Independently of Effects on Reactive Oxygen Species." Neuroscience 94:2 (1999): 571--577. <http://www.ncbi.nlm.nih.gov/pubmed/10579217>

5.a. b. Hipkiss, A.R., C. Brownson. "A Possible New Role for the Anti-ageing Peptide Carnosine." Cell Mol Life Sci 57:5 (2000): 747--753. <http://www.ncbi.nlm.nih.gov/pubmed/10892341>

6. Asif, M., J. Egan, S. Vasan, et al. "An Advanced Glycation Endproduct Cross-link Breaker Can Reverse Age-related Increases in Myocardial Stiffness." Proc Natl Acad Sci USA 97:6 (March 2000): 2809--2813. <http://www.ncbi.nlm.nih.gov/pubmed/10706607>

7. Liu, J., M.R. Masurekar, D.E. Vatner, et al. "Glycation End-product Cross-link Breaker Reduces Collagen and Improves Cardiac Function in Aging Diabetic Heart." Am J Physiol Heart Circ Physiol 285:6 (December 2003): H2587--H2591. <http://www.ncbi.nlm.nih.gov/pubmed/12946933>

8. Preston, J.E., A.R. Hipkiss, D.T. Himsworth, et al. "Toxic Effects of Beta-amyloid(25-35) on Immortalised Rat Brain Endothelial Cell: Protection by Carnosine, Homocarnosine and Beta-alanine." Neurosci Lett 242:2 (February 1998): 105--108. <http://www.ncbi.nlm.nih.gov/pubmed/9533405>

9. Dennis J. Selkoe "Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid ß-protein." Journal of Alzheimer's Disease. Volume 3, Number 1, February 2001 75-81. <http://www.j-alz.com/issues/3/3(1)/selkoe_p75.pdf>

10. Quinn, P., A.A. Boldyrev, et al. "Carnosine: Its Properties, Functions and Potential Therapeutic Applications." Molec Aspects Med 13 (1992): 379--444. <http://www.ncbi.nlm.nih.gov/pubmed/9765790>

11. Quinn. Carnosine: Its Properties

12. Rosick, Edward R. "How Carnosine Protects Against Age-Related Disease." Life  Extension Magazine (January 2006). <www.lef.org/magazine/mag 2006/jan2006_report_carnosine_02.htm.>

13.  Wu XH, Ding MP, Zhu-Ge ZB, et al. "Carnosine, a precursor of histidine, ameliorates pentylenetetrazole-induced kindled seizures in rat." Neurosci Lett. 2006 May 29;400(1-2):146-9. Epub 2006 Mar 3. <http://www.ncbi.nlm.nih.gov/pubmed/16515835>

14. Stvolinsky S, Antipin M, Meguro K, Sato T, Abe H, Boldyrev A. "Effect of carnosine and its Trolox-modified derivatives on life span of Drosophila melanogaster." Rejuvenation Res. 2010 Aug;13(4):453-7. <http://www.ncbi.nlm.nih.gov/pubmed/20681748>

15. Nagai K, Tanida M, Niijima A, et al. "Role of L: -carnosine in the control of blood glucose, blood pressure, thermogenesis, and lipolysis by autonomic nerves in rats: involvement of the circadian clock and histamine." Amino Acids. 2012 Jul;43(1):97-109. Epub 2012 Feb 25. <http://www.ncbi.nlm.nih.gov/pubmed/22367578>

16. McFarland. Retardation.

17. Kilis-Pstrusinska K. "Carnosine, carnosinase and kidney diseases." Postepy Hig Med Dosw (Online). 2012 Apr 20;66:215-23. <http://www.phmd.pl/fulltxt.php?ICID=991600>

18. Janssen B, Hohenadel D, Brinkkoetter P, et al. "Carnosine as a protective factor in diabetic nephropathy: association with a leucine repeat of the carnosinase gene CNDP1." Diabetes. 2005 Aug;54(8):2320-7. <http://www.ncbi.nlm.nih.gov/pubmed/16046297>

19. Francesco Attanasio, Sebastiano Cataldo, et al. "Protective Effects of l- and d-Carnosine on a-Crystallin Amyloid Fibril Formation: Implications for Cataract Disease." Biochemistry, 2009, 48 (27), pp 6522--6531 <http://www.ncbi.nlm.nih.gov/pubmed/19441807>

20. Sibylle Sauerho, Gang Yuan, Gerald Stefan Braun. "L-Carnosine, a Substrate of Carnosinase-1, Influences Glucose Metabolism." Diabetes October 2007 56:2425-2432 <http://diabetes.diabetesjournals.org/content/56/10/2425.full.pdf>

21. Rashid I, van Reyk DM, Davies MJ. "Carnosine and its constituents inhibit glycation of low-density lipoproteins that promotes foam cell formation in vitro." FEBS Lett. 2007 Mar 6;581(5):1067-70. <http://www.ncbi.nlm.nih.gov/pubmed/17316626>

22. Stvolinsky SL, Dobrota D. "Anti-ischemic activity of carnosine. Biochemistry (Mosc)". 2000 Jul;65(7):849-55. <http://www.ncbi.nlm.nih.gov/pubmed/9113734>

23. Zaloga GP, Roberts PR, Black KW, et al. "Carnosine is a novel peptide modulator of intracellular calcium and contractility in cardiac cells." Am J Physiol. 1997;272(1 Pt 2):H462-8.  <http://www.ncbi.nlm.nih.gov/pubmed/9038968>

24. Ansurudeen I, Sunkari VG, Grünler J, et al."Carnosine enhances diabetic wound healing in the db/db mouse model of type 2 diabetes." Amino Acids. 2012 Jul;43(1):127-34. Epub 2012 Mar 24. <http://www.ncbi.nlm.nih.gov/pubmed/22451275>

25. Naghshvar F, Abianeh SM, Ahmadashrafi S, Hosseinimehr SJ. "Chemoprotective effects of carnosine against genotoxicity induced by cyclophosphamide in mice bone marrow cells."Cell Biochem Funct. 2012 Apr 26. <http://www.ncbi.nlm.nih.gov/pubmed/22535690>

26. Hyland P, Duggan O, Hipkiss A, Barnett C, Barnett Y. "The effects of carnosine on oxidative DNA damage levels and in vitro life span in human peripheral blood derived CD4+T cell clones." Mech Ageing Dev. 2000 Dec 20;121(1-3):203-15. <http://www.ncbi.nlm.nih.gov/pubmed/11164474>

27. Renner C, Zemitzsch N, Fuchs B, et al. "Carnosine retards tumor growth in vivo in an NIH3T3-HER2/neu mouse model." Mol Cancer. 2010;9:2. <http://www.ncbi.nlm.nih.gov/pubmed/20053283>

28. Chuang CH, Hu ML. "L-carnosine inhibits metastasis of SK-Hep-1 cells by inhibition of matrix metaoproteinase-9 expression and induction of an antimetastatic gene, nm23-H1." Nutr Cancer. 2008;60(4):526-33. <http://www.ncbi.nlm.nih.gov/pubmed/18584487>

29. Baykara B, Cilaker Micili S, Tugyan K. "The protective effects of carnosine in alcohol-induced hepatic injury in rats."Toxicol Ind Health. 2012 Jun 1. <http://www.ncbi.nlm.nih.gov/pubmed/22661399>

30. Ron Kohen, Yorihiro Yamamoto, Kenneth C. Cundy, Bruce N. Ames. "Antioxidant activity of carnosine, homocarnosine, and anserine present in muscle and brain." Proc. NatI. Acad. Sci. USA Vol. 85, pp. 3175-3179, May 1988. <http://www.pnas.org/content/85/9/3175.full.pdf>

31. Fleisher-Berkovich S, Abramovitch-Dahan C, Ben-Shabat S, Apte R, Beit-Yannai E. "Inhibitory effect of carnosine and N-acetyl carnosine on LPS-induced microglial oxidative stress and inflammation." Peptides. 2009 Jul;30(7):1306-12. Epub 2009 Apr 10. <http://www.ncbi.nlm.nih.gov/pubmed/19540429>

32. Charles Eric. Brown, William E. Antholine. "Chelation chemistry of carnosine. Evidence that mixed complexes may occur in vivo." J. Phys. Chem., 1979, 83 (26), pp 3314--3319. <http://pubs.acs.org/doi/abs/10.1021/j100489a002>

33. Fonteh AN, Harrington RJ, Tsai A, Liao P, Harrington MG. "Free amino acid and dipeptide changes in the body fluids from Alzheimer's disease subjects." Amino Acids. 2007 Feb;32(2):213-24. <http://www.ncbi.nlm.nih.gov/pubmed/17031479>

34. Hipkiss AR. "Could carnosine or related structures suppress Alzheimer's disease?" J Alzheimers Dis. 2007 May;11(2):229-40. <http://www.ncbi.nlm.nih.gov/pubmed/17522447>

35. Tsai SJ, Kuo WW, Liu WH, Yin MC. "Antioxidative and anti-inflammatory protection from carnosine in the striatum of MPTP-treated mice." J Agric Food Chem. 2010 Oct 6. <http://www.ncbi.nlm.nih.gov/pubmed/20925384>


Instructions

Take 1-2 capsules of Ever Young™ with or without food, three times daily.

In rare cases, minor side effects may include mild headaches, muscle tension, or insomnia. If you experience any such side effects, adjust dosage accordingly.

Note: Because Acetyl-L-Carnitine (a key ingredient in Ever Young™) is made with acetic acid, bottles of Ever Young™ may have a vinegar-like smell that can range from very mild to quite strong.

Supplement Facts

Serving Size: 2 Vegetarian Capsules
Servings per Container: 90
Amount per Serving: 1000 mg
Container Size: 180 Capsules
Strength: 500 mg
Click ingredient for more information
Amount Per Serving % Daily Value
L-Carnosine 500 mg N/A*
Acetyl-L-Carnitine HCL 400 mg N/A*
DMAE (Dimethylaminoethanol) bitartrate [providing 37% DMAE (29.6 mg)] 80 mg N/A*
Ionic Trace Minerals 20 mg N/A*
Other ingredients: Silicon Dioxide, Vegetable Stearate, Vegetable Gelatin
All ingredients are either domestically sourced or selectively imported
* Daily Value Not Established

No materials used to produce this product are derived from or contain any Genetically Modified Organisms (GMOs)

All Vegan and Vegetarian Formula

L-Carnosine

L-carnosine is a naturally occurring combination of two amino acids, alanine and histadine. A series of astonishing experiments done in Australia proved that carnosine rejuvenates cells as they approach the end of their life cycle. Cells cultured with carnosine lived longer and retained their youthful appearance and growth patterns. In fact, the studies showed that carnosine as an anti-aging nutritional supplement can actually REVERSE the signs of aging in older cells. A Russian study on mice has shown that mice given carnosine are twice as likely to reach their maximum lifespan as untreated mice. The carnosine also significantly reduced the outward "signs of old age." In effect, carnosine made the mice look younger.

Quite simply, carnosine is one of the most powerful antioxidants known, especially for anti aging nutrition. It's a great heavy-metal scavenger. It's a powerful auto-regulator. And this anti-aging supplement stands alone when it comes to helping with protein glycation or cross-linking.

In addition, carnosine has been proven to help reduce cell damage caused by beta amyloid, one of the prime protein risk factors for Alzheimer's. The presence of beta amyloid leads to damage to the nerves and arteries of the brain. Carnosine blocks and inactivates beta amyloid. In effect, this health supplement protects neural tissues against dementia.

Carnosine levels in our body directly correlate with both the length and quality of our lives. And since carnosine levels decline with age, supplementation with carnosine represents one of the most powerful things you can do to hold back the ravages of old age.

Acetyl-L-Carnitine HCL

Although your body can synthesize L-carnitine in the liver, it depends on outside sources (meat being a primary source) to fulfill its requirements. This can present a problem for vegetarians who don’t use a Carnitine health supplement since L-carnitine performs several key functions in the human body. For one, Carnitine can improve the functioning of the immune system by enhancing the ability of macrophages to function as phagocytes. And it can improve the functioning of muscle tissue. In fact, Carnitine has been shown to increase running speed when given prior to exercise. Carnitine also plays a major factor in cellular energy production by shuttling fatty acids from the main cell body into the mitochondria (the cell's energy factories) so that the fats can be oxidized for energy. Without carnitine, fatty acids cannot easily enter the mitochondria.

There is, however, a specialized form of L-carnitine known as acetyl-L-carnitine (ALC) that is often deficient even in meat eaters and that performs virtually all of the same functions – but better. For example, in terms of cellular energy production, in addition to shuttling fatty acids into cell mitochondria, ALC provides acetyl groups from which Acetyl-Coenzyme A (a key metabolic intermediate) can be regenerated, thereby facilitating the transport of metabolic energy and boosting mitochondrial activity. But beyond that, the addition of the acetyl group makes ALC water soluble, which enables it not only to diffuse easily across the inner wall of the mitochondria but also to cross all cell membranes more easily. In other words, ALC reaches parts of the body where L-carnitine cannot go. In particular, ALC readily crosses the blood/brain barrier, where it provides a number of specialized neurological functions. For example, it can:

  • Facilitate both the release and synthesis of acetylcholine, a key brain biochemical.
  • Increase the brain's levels of choline acetylase.
  • Enhance the release of dopamine and improve the binding of dopamine to dopamine receptors.
  • Protect the neurons of the optic nerve and the occipital cortex of the brain.

In addition, studies have shown that acetyl-L-carnitine can slow down the deterioration in mental function associated with Alzheimer's along with slow its progression. Part of this is a result of its ability to shield neurons from the toxicity of beta amyloid protein. As a result:

  • ALC improves alertness in Alzheimer's patients.
  • Improves attention span.
  • And it increases short term memory.

Through its action on dopamine (a chemical messenger used between nerve cells) and dopamine receptors, ALC seems to play a major role in minimizing the symptoms of Parkinson's.

  • ALC enhances the release of dopamine from dopaminergic neurons and improves the binding of dopamine to dopamine receptors.
  • ALC retards the decline in the number of dopamine receptors that occurs as part of the normal aging process and (more rapidly) with the onset of Parkinson's. In fact, many researchers believe that Parkinson's may be caused by a deficiency of dopamine.
  • And ALC inhibits tremors.

And acetyl-L-carnitine may even play a role in helping with MS.

  • ALC inhibits (and possibly reverses) the degeneration of myelin sheaths.

But most of all, acetyl-L-carnitine just helps slow down the aging process of the brain, making it a key ingredient in any anti-aging supplement:

  • ALC retards the inevitable decline in the number of glucocorticoid receptors that occurs with aging.
  • It retards the age-related deterioration of the hippocampus.
  • It retards the inevitable decline in the number of nerve growth factor receptors that occurs as we age.
  • It stimulates and maintains the growth of new neurons within the brain (both independently of Nerve Growth Factor (NGF) and as a result of preserving NGF).
  • ALC protects the NMDA receptors in the brain from age-related decline.
  • ALC inhibits the excessive release of adrenalin in response to stress and inhibits the depletion of luteinizing hormone releasing hormones and testosterone that occurs as a result of excessive stress.
  • And ALC enhances the function of cytochrome oxidase, an essential enzyme of the Electron Transport System.

The mind boosting effect of acetyl-L-carnitine is often noticed within a few hours of taking this anti-aging nutrition -- or even within an hour. Most people report feeling mentally sharper, having more focus, and being more alert. Some find a mild mood enhancement. More specifically:

  • ALC improves learning ability along with both short term and long term memory.
  • It improves mood by 53%.
  • It both improves the quality of and reduces the need for sleep.
  • It improves verbal fluency.
  • And ALC improves hand eye coordination by some 300-400%.

DMAE (Dimethylaminoethanol) bitartrate [providing 37% DMAE (29.6 mg)]

By any definition, DMAE is the perfect companion to carnosine in an anti-aging supplement. First, it reinforces carnosine's own anti-aging properties. Then, it provides a whole series of complementary benefits of its own. DMAE is short for (dimethylaminoethanol), a naturally-occurring nutrient that enhances acetylcholine (ACh) synthesis. Adequate levels of ACh are important for proper memory function. Normally found in small amounts in our brains, DMAE has been shown to remarkably enhance brain function when used as a dietary supplement in clinical studies.

One of the prime actions of DMAE is that it flushes accumulated lipofuscin from your body – from the neurons in your brain, from your skin, and from all other organs. It also complements carnosine in that DMAE on its own has been shown to inhibit and reverse the Cross-Linking of proteins and extend lifespan.

Numerous scientific studies now show that DMAE can help:

  • Increase Acetylcholine levels and RNA levels in the brain
  • Stimulate mental activity
  • Increase attention span
  • Increase alertness
  • Increase intelligence (especially in children)
  • Increase energy levels
  • Provide a mild, safe tonic effect
  • Stimulate the central nervous system
  • Address anxiety
  • Elevate mood in general
  • Alleviate behavioral problems and hyperactivity associated with Attention Deficit Disorder
  • Increase motivation and reduce apathy in persons suffering from depression
  • Induce sounder sleep
  • Over time reduce the amount of sleep required by about 1 hour per night
  • Intensify dreams tremendously. (Even more so when you take it along with a large dose of phosphatidyl choline -- a key component of lecithin)
  • Cause dreams to become more lucid
  • Increase willpower
  • Decrease the incidence and severity of hangovers in people who consume excessive amounts of alcohol

Ionic Trace Minerals

Ionic minerals are added to many formulas to increase the bio-electric activity level of the ingredients in the formula and sustain their activity for a significantly longer period of time.

Ionic merely means that the minerals are broken down to their absolutely smallest form.

Silicon Dioxide

Vegetable Stearate

Vegetable Gelatin

Write Your Own Review
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  Do you use magnesium stearate in any of your products?
  Is there a connection between L-Carnitine and the bacteria TMAO that I've been hearing about?
  I notice I can't take Ever Young before bed, but I need to take these 3 times a day. Can I double up on one dosage?
  I am under 30, can I still benefit from an anti-aging health supplement such as Ever Young?
  Does Ever Young work similar to carnitine bodybuilding health supplements?
  Are there any problems in mixing the two amino acids L-carnosine and Acetyl L carnitine?
  L-Carnosine is known to increase cell life span & division. Are there any contraindications for cancer patients?
  Where is the L-Carnosine in the Ever Young found or extracted prior to its supplement form, is it plant-based?
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Disclaimer: *THE ABOVE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. NEITHER THE INGREDIENTS NOR THE PRODUCT DISCUSSED ON THIS PAGE ARE INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE.