Liver Tincture Additional Information


Ingredient Supporting Studies:

  1. Laekeman G, De Coster S, De Meyer K. "St. Mary's Thistle: an overview."  J Pharm Belg. 2003;58(1):28-31.
  2. McClure J, Lovelace ES, Elahi S, Maurice NJ, et al. "Silibinin inhibits HIV-1 infection by reducing cellular activation and proliferation."PLoS One. 2012;7(7):e41832.
  3. Huseini HF, Larijani B, Heshmat R, Fakhrzadeh H, et al. "The efficacy of Silybum marianum (L.) Gaertn. (silymarin) in the treatment of type II diabetes: a randomized, double-blind, placebo-controlled, clinical trial." Phytother Res. 2006 Dec;20(12):1036-9.
  4. Simons JM, Hart BA, Ip Vai Ching TR, Van Dijk H, Labadie RP. "Metabolic activation of natural phenols into selective oxidative burst agonists by activated human neutrophils." Free Radic Biol Med 1990;8:251-258.
  5. Stuppner H, Wagner H. "New cucurbitacin glycosides from Picrorhiza kurroa." Planta Medica 1989;55:559.
  6. Visen PK, Saraswat B, Dhawan BN. "Curative effect of picroliv on primary cultured rat hepatocytes against different hepatotoxins: an in vitro study." J Pharmacol Toxicol Methods 1998;40:173-179.
  7. Rastogi R, Srivastava AK, Rastogi AK. "Biochemical changes induced in liver and serum aflatoxin B1-treated male wistar rats: preventive effect of picroliv." Pharmacol Toxicol 2001;88:53-58.
  8. Singh AK, Mani H, Seth P. "Picroliv preconditioning protects the rat liver against ischemia-reperfusion injury." Eur J Pharmacol 2000;395:229-239.
  9. Dwivedi Y, Rastogi R, Garg NK, et al. "Effects of picroliv, the active principle of Picrorhiza kurroa, on biochemical changes in rat liver poisoned by Amanita phalloides." Zhongguo Yao Li Xue Bao 1992;13:197-200.
  10. Singh V, Kapoor NK, Dhawan BN. "Effect of picroliv on protein and nucleic acid synthesis." Indian J Exp Biol 1992;30:68-69.
  11. Saraswat B, Visen PK, Patnaik GK, Dhawan BN. "Ex vivo and in vivo investigations of picroliv from Picrorhiza kurroa in an alcohol intoxication model in rats." J Ethnopharmacol 1999;66:263-269.
  12. Mehrotra R, Rawat S, Kulshreshtha DK, et al. "In vitro studies on the effect of certain natural products against hepatitis B virus." Indian J Med Res 1990;92:133-138.
  13. Vaidya AB, Antarkar DS, Doshi JC, et al. "Picrorhiza kurroa (Kutaki) Royle ex Benth as a hepatoprotective agent--experimental and clinical studies." J Postgrad Med 1996;42:105-108.;year=1996;volume=42;issue=4;spage=105;epage=8;aulast=Vaidya
  14. Rajkumar V, Guha G, Kumar RA. "Antioxidant and anti-neoplastic activities of Picrorhiza kurroa extracts." Food Chem Toxicol. 2011 Feb;49(2):363-9.
  15. Rajeshkumar NV, Kuttan R. "Inhibition of N-nitrosodiethylamine-induced hepatocarcinogenesis by Picroliv." J Exp Clin Cancer Res. 2000 Dec;19(4):459-65.
  16. Rajeshkumar NV, Kuttan R. "Protective effect of Picroliv, the active constituent of Picrorhiza kurroa, against chemical carcinogenesis in mice." Teratog Carcinog Mutagen. 2001;21(4):303-13.
  17. Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K. "Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora." J Agric Food Chem. 2012 Dec 12;60(49):12074-81.
  18. Min BS, Miyashiro H, Hattori M. "Inhibitory effects of quinones on RNase H activity associated with HIV-1 reverse transcriptase." Phytother Res. 2002 Mar;16 Suppl 1:S57-62.
  19. Anulewicz AC, McCullough DG, Cappaert DL, Poland TM. "Host range of the emerald ash borer (Agrilus planipennis Fairmaire) (Coleoptera: Buprestidae) in North America: results of multiple-choice field experiments." Environ Entomol. 2008 Feb;37(1):230-41.
  20. John Christopher. "Black Walnut Tincture." Dr. Christopher's Herbal Legacy. (Accessed 5 May 2013.)
  21. Atta AH, Elkoly TA, Mouneir SM, Kamel G, et al. "Hepatoprotective Effect of Methanol Extracts of Zingiber officinale and Cichorium intybus." Indian J Pharm Sci. 2010 Sep-Oct; 72(5): 564--570.
  22. assan HA, Yousef MI. Ameliorating effect of chicory (Cichorium intybus L.)-supplemented diet against nitrosamine precursors-induced liver injury and oxidative stress in male rats." Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2163-9.
  23. Kim M, Shin HK. "The water-soluble extract of chicory influences serum and liver lipid concentrations, cecal short-chain fatty acid concentrations and fecal lipid excretion in rats." J Nutr. 1998 Oct;128(10):1731-6.
  24. Schmidt BM, Ilic N, Poulev A, Raskin I. "Toxicological evaluation of a chicory root extract." Food Chem Toxicol. 2007 Jul;45(7):1131-9.
  25. Mahesh A, Jeyachandran R, Cindrella L, Thangadurai D, et al. "Hepatocurative potential of sesquiterpene lactones of Taraxacum officinale on carbon tetrachloride induced liver toxicity in mice." Acta Biol Hung. 2010 Jun;61(2):175-90. doi: 10.1556/ABiol.61.2010.2.6.
  26. Domitrovic R, Jakovac H, Romic Z, Rahelic D, Tadic Z. "Antifibrotic activity of Taraxacum officinale root in carbon tetrachloride-induced liver damage in mice." J Ethnopharmacol. 2010 Aug 9;130(3):569-77.
  27. Atta AH, Elkoly TA, Mouneir SM, Kamel G, et al.
  28. Leake I. "Nausea and vomiting: Getting to the root of the antiemetic effects of ginger. "Nat Rev Gastroenterol Hepatol. 2013 Mar 26.
  29. Chao J, Liao JW, Peng WH, Lee MS, et al. "Antioxidant, Analgesic, Anti-Inflammatory, and Hepatoprotective Effects of the Ethanol Extract of Mahonia oiwakensis Stem." Int J Mol Sci. 2013 Jan 30;14(2):2928-45.
  30. Chao J, Lee MS, Amagaya S, Liao JW, et al. "Hepatoprotective effect of shidagonglao on acute liver injury induced by carbon tetrachloride." Am J Chin Med. 2009;37(6):1085-97.
  31. Stermitz FR, Lorenz P, Tawara JN, Zenewicz LA, Lewis K. "Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5'-methoxyhydnocarpin, a multidrug pump inhibitor". Proc. Natl. Acad. Sci. U.S.A. 97 (4): 1433--7.
  32. Englisch W, Beckers C, Unkauf M, et al. "Efficacy of artichoke dry extract in patients with hyperlipoproteinemia." Arzneimittelforschung. 2000;50:260-265.
  33. Bundy R, Walker AF, Middleton RW, et al. "Artichoke leaf extract (Cynara scolymus) reduces plasma cholesterol in otherwise healthy hypercholesterolemic adults: A randomized, double blind placebo controlled trial." Phytomedicine. 2008 Apr 16.
  34. Qiang Z, Lee SO, Ye Z, Wu X, Hendrich S. "Artichoke extract lowered plasma cholesterol and increased fecal bile acids in Golden Syrian hamsters." Phytother Res. 2012 Jul;26(7):1048-52. doi: 10.1002/ptr.3698. Epub 2011 Dec 20.
  35. Jiang WX, Xue BY. "[Hepatoprotective effects of Gentiana scabra on the acute liver injuries in mice]. Zhongguo Zhong Yao Za Zhi. 2005 Jul;30(14):1105-7.
  36. Oztürk N, Herekman-Demir T, Oztürk Y, Bozan B, Baser KH. "Choleretic activity of Gentiana lutea ssp. symphyandra in rats." Phytomedicine. 1998 Aug;5(4):283-8. doi: 10.1016/S0944-7113(98)80067-6.
  37. Tang ZM, Peng M, Zhan CJ. "[Screening 20 Chinese herbs often used for clearing heat and dissipating toxin with nude mice model of hepatitis C viral infection]." Zhongguo Zhong Xi Yi Jie He Za Zhi. 2003 Jun;23(6):447-8.
  38. Kara Rogers. "artemisinin" Encyclopaedia Britannica. (Accessed 6 May 2013.)
  39. "Update on artemisinin resistance." April 2012. World Health Organization. (Accessed 6 May 2013.)
  40. Ibrahim AN. "Comparison of in vitro activity of metronidazole and garlic-based product (Tomex®) on Trichomonas vaginalis." Parasitol Res. 2013 May;112(5):2063-7.
  41. Mantawy MM, Ali HF, Rizk MZ. "Therapeutic effects of Allium sativum and Allium cepa in Schistosoma mansoni experimental infection." Rev Inst Med Trop Sao Paulo. 2011 May-Jun;53(3):155-63.
  42. Jean Noon. " Controlling Sheep Parasites with Garlic Juice." 2004. MOFGA. (Accessed 6 may 2013.)