Warp Speed Additional Information


Ingredient Supporting Studies:

  1. Pingali U, Pilli R, Fatima N. "Effect of standardized aqueous extract of Withania somnifera on tests of cognitive and psychomotor performance in healthy human participants." Pharmacognosy Res. 2014 Jan;6(1):12-8. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897003/
  2. Ahmed ME, et al. Attenuation of oxidative damage-associated cognitive decline by Withania somnifera in rat model of streptozotocin-induced cognitive impairment.  Protoplasma. (2013). http://www.ncbi.nlm.nih.gov/pubmed/23340606
  3. Archana R, Namasivayam A. "Antistressor effect of Withania somnifera." J Ethnopharmacol. 1999 Jan;64(1):91-3. http://www.ncbi.nlm.nih.gov/pubmed/10075127
  4. An Alternative Treatment for Anxiety: A Systematic Review of Human Trial Results Reported for the Ayurvedic Herb Ashwagandha (Withania somnifera). J Altern Complement Med. 2014 Nov 18. http://online.liebertpub.com/doi/pdf/10.1089/acm.2014.0177
  5. Chandrasekhar K1, Kapoor J, Anishetty S. "A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults." Indian J Psychol Med. 2012 Jul;34(3):255-62. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/
  6. Maity T, Adhikari A, Bhattacharya K, Biswas S, et al. "A study on evalution of antidepressant effect of imipramine adjunct with Aswagandha and Bramhi." Nepal Med Coll J. 2011 Dec;13(4):250-3. http://www.ncbi.nlm.nih.gov/pubmed/23016473
  7. Shenoy S1, Chaskar U, Sandhu JS, Paadhi MM. "Effects of eight-week supplementation of Ashwagandha on cardiorespiratory endurance in elite Indian cyclists." J Ayurveda Integr Med. 2012 Oct;3(4):209-14. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545242/
  8. Biswajit Auddy, Jayaram Hazra, Achin Mitra, Bruce Abedon, Shibnath Ghosal. "A standardized Withania somnifera extract significantly reduces stress-related parameters in chronically stressed humans: a double-blind, randomized, placebo-controlled study." JANA Vol 11, No 1. 2008. http://www.lifeforce.net/pdfs/withania_review.pdf
  9. K. Chandrasekhar, Jyoti Kapoor, and Sridhar Anishetty1. "A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults." Indian J Psychol Med. 2012 Jul-Sep; 34(3): 255-262.
  10. Gupta A, Mahdi AA, Shukla KK, Ahmad MK, et al. "Efficacy of Withania somnifera on seminal plasma metabolites of infertile males: a proton NMR study at 800 MHz." J Ethnopharmacol. 2013 Aug 26;149(1):208-14. http://www.ncbi.nlm.nih.gov/pubmed/23796876
  11. Agarwal R, Diwanay S, Patki P, Patwardhan B. "Studies on immunomodulatory activity of Withania somnifera (Ashwagandha) extracts in experimental immune inflammation." Journal of Ethnopharmacology. 1999;67:27-35. http://www.ncbi.nlm.nih.gov/pubmed/10616957
  12. Barua A1, Bradaric MJ, Bitterman P, Abramowicz JS, et al. "Dietary supplementation of Ashwagandha (Withania somnifera, Dunal) enhances NK cell function in ovarian tumors in the laying hen model of spontaneous ovarian cancer." Am J Reprod Immunol. 2013 Dec;70(6):538-50. http://www.ncbi.nlm.nih.gov/pubmed/24188693

  13. Kuchewar VV, Borkar MA, Nisargandha MA. "Evaluation of antioxidant potential of Rasayana drugs in healthy human volunteers." Ayu. 2014 Jan;35(1):46-9. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213967/
  14. Nile SH, Park SW. "HPTLC Analysis, Antioxidant and Antigout Activity of Indian Plants." Iran J Pharm Res. 2014 Spring;13(2):531-9. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157028/
  15. Ojha S, Alkaabi J, Amir N, Sheikh A, et al. "Withania coagulans fruit extract reduces oxidative stress and inflammation in kidneys of streptozotocin-induced diabetic rats." Oxid Med Cell Longev. 2014;2014:201436. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177777/
  16. Heyninck K, Lahtela-Kakkonen M, Van der Veken P, et al. "Withaferin A inhibits NF-kappaB activation by targeting cysteine 179 in IKKß." Biochem Pharmacol. 2014 Oct 15;91(4):501-9. http://www.ncbi.nlm.nih.gov/pubmed/25159986
  17. Tomoharu Kuboyama, Chihiro Tohda,Katsuko Komatsu. "Neuritic regeneration and synaptic reconstruction induced by withanolide A." British Journal of Pharmacology (2005) 144, 961--971 http://8-12hz.com/media/Neuritic-regeneration-and-synaptic-reconstruction-induced-by-withanolide-A.pdf
  18. Ranjeet Kumar1, Kuldeep Gupta1, Kopal Saharia1, et al. "Withania somnifera root extract extends lifespan of Caenorhabditis elegans." Annals of Neurosciences, Volume 20, Issue 1 (January), 2013.  http://annalsofneurosciences.org/journal/index.php/annal/article/view/472/2202
  19. Stough C, Lloyd J, Clarke J, Downey LA, Hutchison CW, et al. "The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects." Psychopharmacology (Berl). 2001 Aug;156(4):481-4. http://www.ncbi.nlm.nih.gov/pubmed/11498727
  20. Calabrese C, Gregory WL, Leo M, Kraemer D, Bone K, Oken B. "Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial." J Altern Complement Med. 2008 Jul;14(6):707-13. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153866/
  21. Stough C, Downey LA, Lloyd J, Silber B, Redman S, et al. "Examining the nootropic effects of a special extract of Bacopa monniera on human cognitive functioning: 90 day double-blind placebo-controlled randomized trial." Phytother Res. 2008 Dec;22(12):1629-34. http://www.ncbi.nlm.nih.gov/pubmed/18683852
  22. Stough, Lloyd J
  23. Calabrese
  24. Annette Morgan. "Grey Matters: Does Bacopa monnieri Improve Memory Performance in Older Persons?" Department of Nursing and Health Care Practices, Southern Cross University. July, 2006. http://epubs.scu.edu.au/cgi/viewcontent.cgi?article=1061&context=theses
  25. Rastogi M1, Ojha RP, Prabu PC, Devi BP, et al. "Prevention of age-associated neurodegeneration and promotion of healthy brain ageing in female Wistar rats by long term use of bacosides." Biogerontology. 2012 Apr;13(2):183-95. http://www.ncbi.nlm.nih.gov/pubmed/22143822
  26. Dave UP, Dingankar SR, Saxena VS, Joseph JA, et al. "An open-label study to elucidate the effects of standardized Bacopa monnieri extract in the management of symptoms of attention-deficit hyperactivity disorder in children." Adv Mind Body Med. 2014 Spring;28(2):10-5.  http://www.ncbi.nlm.nih.gov/pubmed/24682000
  27. Khan MB1, Ahmad M, Ahmad S, Ishrat T, et al. "Bacopa monniera ameliorates cognitive impairment and neurodegeneration induced by intracerebroventricular-streptozotocin in rat: behavioral, biochemical, immunohistochemical and histopathological evidences." Metab Brain Dis. 2014 Jul 19. http://www.ncbi.nlm.nih.gov/pubmed/25037167
  28. Sadhu A1, Upadhyay P, Agrawal A, Ilango K, et al. "Management of cognitive determinants in senile dementia of Alzheimer's type: therapeutic potential of a novel polyherbal drug product." Clin Drug Investig. 2014 Dec;34(12):857-69. http://www.ncbi.nlm.nih.gov/pubmed/25316430
  29. Dhanasekaran M, Tjarakan B, Holcomb L, et al. "Neuroprotective mechanisms of ayurvedic antidementia botanical Bacopa monniera." Phytother Res. 2007 Oct;21(10):965-9. http://onlinelibrary.wiley.com/doi/10.1002/ptr.2195/abstract
  30. Bhandari P, Kumar N, Singh B, Kaul VK. "Bacosterol glycoside, a new 13,14-seco-steroid glycoside from Bacopa monnieri." Chem Pharm Bull (Tokyo). 2006 Feb;54(2):240-1. https://www.jstage.jst.go.jp/article/cpb/54/2/54_2_240/_pdf
  31. Deepak M1, Sangli GK, Arun PC, Amit A. "Quantitative determination of the major saponin mixture bacoside A in Bacopa monnieri by HPLC." Phytochem Anal. 2005 Jan-Feb;16(1):24-9. http://www.ncbi.nlm.nih.gov/pubmed/15688952

  32. Sharma R, Chaturvedi C, Tewari PV. "Efficacy of Bacopa monierra in revitalizing intellectual functions in children." J Rees Edu Ind Med 1987:1-12.
  33. Vollala VR1, Upadhya S, Nayak S. "Enhanced dendritic arborization of amygdala neurons during growth spurt periods in rats orally intubated with Bacopa monniera extract."Anat Sci Int. 2011 Dec;86(4):179-88. http://www.ncbi.nlm.nih.gov/pubmed/21409525
  34. Guo S1, Yan J, Yang T, Yang X, Bezard E, Zhao B. "Protective effects of green tea polyphenols in the 6-OHDA rat model of Parkinson's disease through inhibition of ROS-NO pathway."  Biol Psychiatry. 2007 Dec 15;62(12):1353-62. http://www.ncbi.nlm.nih.gov/pubmed/17624318
  35. 1.S.-J. Hyung, A. S. DeToma, J. R. Brender, S. Lee, S. Vivekanandan, A. Kochi, J.-S. Choi, A. Ramamoorthy, B. T. Ruotolo, M. H. Lim. Insights into antiamyloidogenic properties of the green tea extract (-)-epigallocatechin-3-gallate toward metal-associated amyloid-  species. Proceedings of the National Academy of Sciences, 2013; vol. 110 no. 10. http://www.pnas.org/content/110/10/3743.full
  36. Yu Y, Deng Y, Lu BM, Liu YX, Li J, Bao JK. "Green tea catechins: a fresh flavor to anticancer therapy." Apoptosis. 2014 Jan;19(1):1-18. http://www.ncbi.nlm.nih.gov/pubmed/24081390
  37. Zhang W, Yang P, Gao F, Yang J, Yao K. "Effects of epigallocatechin gallate on the proliferation and apoptosis of the nasopharyngeal carcinoma cell line CNE2." Exp Ther Med. 2014 Dec;8(6):1783-1788. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217784/
  38. Chung FL. "The prevention of lung cancer induced by a tobacco-specific carcinogen in rodents by green and black Tea." Proc Soc Exp Biol Med. 1999 Apr;220(4):244-8. http://www.ncbi.nlm.nih.gov/pubmed/10202397
  39. Russ Mason. "200 mg of Zen, L-Theanine Boosts Alpha Wavss, Promtoes Alert Relaxation." ALTERNATIVE & COMPLEMENTARY THERAPIES. April 2001. http://8-12hz.com/media/200-mg-of-Zen.pdf
  40. Nathan PJ, Lu K, Gray M, Oliver C. "The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent." J Herb Pharmacother. 2006;6(2):21-30. http://www.ncbi.nlm.nih.gov/pubmed/17182482
  41. R.S. Kujur1, Vishakha Singh, Mahendra Ram1, Harlokesh Narayan Yadava2, et al. "Antidiabetic Activity and Phytochemical Screening of Crude Extract of Stevia Rebaudiana in Alloxan-induced Diabetiis Rats." Pharmacognosy Journal Volume 2, Issue 14, September 2010, Pages 27--32. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141138/